Transcriptome profiling identifies genes and pathways deregulated upon floxuridine treatment in colorectal cancer cells harboring GOF mutant p53

Mutation in TP53 is a common genetic alteration in human cancers. Certain tumor associated p53 missense mutants acquire gain-of-function (GOF) properties and confer oncogenic phenotypes including enhanced chemoresistance. The colorectal cancers (CRC) harboring mutant p53 are generally aggressive in...

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Detalles Bibliográficos
Autores principales: Datta, Arindam, Dey, Sanjib, Das, Pijush, Alam, Sk. Kayum, Roychoudhury, Susanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Data in Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832042/
https://www.ncbi.nlm.nih.gov/pubmed/27114909
http://dx.doi.org/10.1016/j.gdata.2016.03.003

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