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T-cell activation is an immune correlate of risk in BCG vaccinated infants

Vaccines to protect against tuberculosis (TB) are urgently needed. We performed a case–control analysis to identify immune correlates of TB disease risk in Bacille Calmette–Guerin (BCG) immunized infants from the MVA85A efficacy trial. Among 53 TB case infants and 205 matched controls, the frequency...

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Detalles Bibliográficos
Autores principales: Fletcher, Helen A., Snowden, Margaret A., Landry, Bernard, Rida, Wasima, Satti, Iman, Harris, Stephanie A., Matsumiya, Magali, Tanner, Rachel, O'Shea, Matthew K., Dheenadhayalan, Veerabadran, Bogardus, Leah, Stockdale, Lisa, Marsay, Leanne, Chomka, Agnieszka, Harrington-Kandt, Rachel, Manjaly-Thomas, Zita-Rose, Naranbhai, Vivek, Stylianou, Elena, Darboe, Fatoumatta, Penn-Nicholson, Adam, Nemes, Elisa, Hatherill, Mark, Hussey, Gregory, Mahomed, Hassan, Tameris, Michele, McClain, J Bruce, Evans, Thomas G., Hanekom, Willem A., Scriba, Thomas J., McShane, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832066/
https://www.ncbi.nlm.nih.gov/pubmed/27068708
http://dx.doi.org/10.1038/ncomms11290

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