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T-cell activation is an immune correlate of risk in BCG vaccinated infants
Vaccines to protect against tuberculosis (TB) are urgently needed. We performed a case–control analysis to identify immune correlates of TB disease risk in Bacille Calmette–Guerin (BCG) immunized infants from the MVA85A efficacy trial. Among 53 TB case infants and 205 matched controls, the frequency...
Autores principales: | Fletcher, Helen A., Snowden, Margaret A., Landry, Bernard, Rida, Wasima, Satti, Iman, Harris, Stephanie A., Matsumiya, Magali, Tanner, Rachel, O'Shea, Matthew K., Dheenadhayalan, Veerabadran, Bogardus, Leah, Stockdale, Lisa, Marsay, Leanne, Chomka, Agnieszka, Harrington-Kandt, Rachel, Manjaly-Thomas, Zita-Rose, Naranbhai, Vivek, Stylianou, Elena, Darboe, Fatoumatta, Penn-Nicholson, Adam, Nemes, Elisa, Hatherill, Mark, Hussey, Gregory, Mahomed, Hassan, Tameris, Michele, McClain, J Bruce, Evans, Thomas G., Hanekom, Willem A., Scriba, Thomas J., McShane, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832066/ https://www.ncbi.nlm.nih.gov/pubmed/27068708 http://dx.doi.org/10.1038/ncomms11290 |
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