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Clec4A4 is a regulatory receptor for dendritic cells that impairs inflammation and T-cell immunity
Dendritic cells (DCs) comprise several subsets that are critically involved in the initiation and regulation of immunity. Clec4A4/DC immunoreceptor 2 (DCIR2) is a C-type lectin receptor (CLR) exclusively expressed on CD8α(−) conventional DCs (cDCs). However, how Clec4A4 controls immune responses thr...
Autores principales: | Uto, Tomofumi, Fukaya, Tomohiro, Takagi, Hideaki, Arimura, Keiichi, Nakamura, Takeshi, Kojima, Naoya, Malissen, Bernard, Sato, Katsuaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832068/ https://www.ncbi.nlm.nih.gov/pubmed/27068492 http://dx.doi.org/10.1038/ncomms11273 |
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