Downregulation of COMMD1 by miR-205 promotes a positive feedback loop for amplifying inflammatory- and stemness-associated properties of cancer cells

Sustained activation of nuclear factor-κB (NF-κB) in cancer cells has been shown to promote inflammation, expansion of cancer stem cell (CSC) population, and tumor development. In contrast, recent studies reveal that CSCs exhibit increased inflammation due to constitutive NF-κB activation; however,...

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Detalles Bibliográficos
Autores principales: Yeh, D-W, Chen, Y-S, Lai, C-Y, Liu, Y-L, Lu, C-H, Lo, J-F, Chen, L, Hsu, L-C, Luo, Y, Xiang, R, Chuang, T-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832103/
https://www.ncbi.nlm.nih.gov/pubmed/26586569
http://dx.doi.org/10.1038/cdd.2015.147

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