Novel Roles for Peroxynitrite in Angiotensin II and CaMKII Signaling

Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) oxidation controls excitability and viability. While hydrogen peroxide (H(2)O(2)) affects Ca(2+)-activated CaMKII in vitro, Angiotensin II (Ang II)-induced CaMKIIδ signaling in cardiomyocytes is Ca(2+) independent and requires NADPH oxidase-deri...

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Detalles Bibliográficos
Autores principales: Zhou, Chaoming, Ramaswamy, Swarna S., Johnson, Derrick E., Vitturi, Dario A., Schopfer, Franciso J., Freeman, Bruce A., Hudmon, Andy, Levitan, Edwin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832198/
https://www.ncbi.nlm.nih.gov/pubmed/27079272
http://dx.doi.org/10.1038/srep23416

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