Cargando…
Uncovering disease mechanisms through network biology in the era of Next Generation Sequencing
Characterizing the behavior of disease genes in the context of biological networks has the potential to shed light on disease mechanisms, and to reveal both new candidate disease genes and therapeutic targets. Previous studies addressing the network properties of disease genes have produced contradi...
Autores principales: | Piñero, Janet, Berenstein, Ariel, Gonzalez-Perez, Abel, Chernomoretz, Ariel, Furlong, Laura I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832203/ https://www.ncbi.nlm.nih.gov/pubmed/27080396 http://dx.doi.org/10.1038/srep24570 |
Ejemplares similares
-
Mining the Modular Structure of Protein Interaction Networks
por: Berenstein, Ariel José, et al.
Publicado: (2015) -
A Multilayer Network Approach for Guiding Drug Repositioning in Neglected Diseases
por: Berenstein, Ariel José, et al.
Publicado: (2016) -
TDR Targets 6: driving drug discovery for human pathogens through intensive chemogenomic data integration
por: Urán Landaburu, Lionel, et al.
Publicado: (2020) -
Using coevolution to improve protein subfamily classification
por: Simonetti, Franco, et al.
Publicado: (2015) -
Reprogramming human A375 amelanotic melanoma cells by catalase overexpression: Upregulation of antioxidant genes correlates with regression of melanoma malignancy and with malignant progression when downregulated
por: Bracalente, Candelaria, et al.
Publicado: (2016)