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Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma

Early detection of the highly aggressive malignancy cholangiocarcinoma (CCA) remains a challenge but has the potential to render the tumor curable by surgical removal. This study evaluates a biomarker panel for the diagnosis of CCA by DNA methylation analyses of biliary brush samples. The methylatio...

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Detalles Bibliográficos
Autores principales: Andresen, Kim, Boberg, Kirsten Muri, Vedeld, Hege Marie, Honne, Hilde, Jebsen, Peter, Hektoen, Merete, Wadsworth, Christopher A., Clausen, Ole Petter, Lundin, Knut E.A., Paulsen, Vemund, Foss, Aksel, Mathisen, Øystein, Aabakken, Lars, Schrumpf, Erik, Lothe, Ragnhild A., Lind, Guro E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832263/
https://www.ncbi.nlm.nih.gov/pubmed/25644509
http://dx.doi.org/10.1002/hep.27707