The presence of prolines in the flanking region of an immunodominant HIV‐2 gag epitope influences the quality and quantity of the epitope generated

Both the recognition of HIV‐infected cells and the immunogenicity of candidate CTL vaccines depend on the presentation of a peptide epitope at the cell surface, which in turn depends on intracellular antigen processing. Differential antigen processing maybe responsible for the differences in both th...

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Detalles Bibliográficos
Autores principales: Jallow, Sabelle, Leligdowicz, Aleksandra, Kramer, Holger B., Onyango, Clayton, Cotten, Matthew, Wright, Cynthia, Whittle, Hilton C., McMichael, Andrew, Dong, Tao, Kessler, Benedikt M., Rowland‐Jones, Sarah L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Antigen Processing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832300/
https://www.ncbi.nlm.nih.gov/pubmed/26018465
http://dx.doi.org/10.1002/eji.201545451

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