Evaluation of Hybridization Capture Versus Amplicon‐Based Methods for Whole‐Exome Sequencing

Next‐generation sequencing has aided characterization of genomic variation. While whole‐genome sequencing may capture all possible mutations, whole‐exome sequencing remains cost‐effective and captures most phenotype‐altering mutations. Initial strategies for exome enrichment utilized a hybridization...

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Detalles Bibliográficos
Autores principales: Samorodnitsky, Eric, Jewell, Benjamin M., Hagopian, Raffi, Miya, Jharna, Wing, Michele R., Lyon, Ezra, Damodaran, Senthilkumar, Bhatt, Darshna, Reeser, Julie W., Datta, Jharna, Roychowdhury, Sameek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832303/
https://www.ncbi.nlm.nih.gov/pubmed/26110913
http://dx.doi.org/10.1002/humu.22825

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