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Development of a stable ERroGFP variant suitable for monitoring redox dynamics in the ER

The endoplasmic reticulum (ER) is an essential organelle for cellular metabolic homeostasis including folding and maturation of secretory and membrane proteins. Disruption of ER proteostasis has been implicated in the pathogenesis of various diseases such as diabetes and neurodegenerative diseases....

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Detalles Bibliográficos
Autores principales: Hoseki, Jun, Oishi, Asami, Fujimura, Takaaki, Sakai, Yasuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832336/
https://www.ncbi.nlm.nih.gov/pubmed/26934978
http://dx.doi.org/10.1042/BSR20160027