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The C‐terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase

Mammalian xanthine oxidoreductase can exist in both dehydrogenase and oxidase forms. Conversion between the two is implicated in such diverse processes as lactation, anti‐bacterial activity, reperfusion injury and a growing number of diseases. We have constructed a variant of the rat liver enzyme th...

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Detalles Bibliográficos
Autores principales: Nishino, Tomoko, Okamoto, Ken, Kawaguchi, Yuko, Matsumura, Tomohiro, Eger, Bryan T., Pai, Emil F., Nishino, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832347/
https://www.ncbi.nlm.nih.gov/pubmed/25817260
http://dx.doi.org/10.1111/febs.13277