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The C‐terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase
Mammalian xanthine oxidoreductase can exist in both dehydrogenase and oxidase forms. Conversion between the two is implicated in such diverse processes as lactation, anti‐bacterial activity, reperfusion injury and a growing number of diseases. We have constructed a variant of the rat liver enzyme th...
Autores principales: | Nishino, Tomoko, Okamoto, Ken, Kawaguchi, Yuko, Matsumura, Tomohiro, Eger, Bryan T., Pai, Emil F., Nishino, Takeshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832347/ https://www.ncbi.nlm.nih.gov/pubmed/25817260 http://dx.doi.org/10.1111/febs.13277 |
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