The use of human sewage screening for community surveillance of hepatitis E virus in the UK

Hepatitis E virus sequences were detected by RT‐PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co‐circulation of multiple variants of HEV‐3, with a pattern of diversity matching that observed in a loca...

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Detalles Bibliográficos
Autores principales: Smith, Donald B., Paddy, Julius O., Simmonds, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832372/
https://www.ncbi.nlm.nih.gov/pubmed/26461450
http://dx.doi.org/10.1002/jmv.24403
Descripción
Sumario:Hepatitis E virus sequences were detected by RT‐PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co‐circulation of multiple variants of HEV‐3, with a pattern of diversity matching that observed in a local cohort of HEV‐infected hepatitis patients. J. Med. Virol. 88:915–918, 2016. © 2015 The Authors. Journal of Medical Virology Published by Wiley Periodicals, Inc.

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