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VEGFR2 Trafficking, Signaling and Proteolysis is Regulated by the Ubiquitin Isopeptidase USP8
Vascular endothelial growth factor A (VEGF‐A) regulates many aspects of vascular function. VEGF‐A binding to vascular endothelial growth factor receptor 2 (VEGFR2) stimulates endothelial signal transduction and regulates multiple cellular responses. Activated VEGFR2 undergoes ubiquitination but the...
Autores principales: | Smith, Gina A., Fearnley, Gareth W., Abdul‐Zani, Izma, Wheatcroft, Stephen B., Tomlinson, Darren C., Harrison, Michael A., Ponnambalam, Sreenivasan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons A/S
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832373/ https://www.ncbi.nlm.nih.gov/pubmed/26459808 http://dx.doi.org/10.1111/tra.12341 |
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