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GacA is essential for Group A S treptococcus and defines a new class of monomeric dTDP‐4‐dehydrorhamnose reductases (RmlD)
The sugar nucleotide dTDP‐L‐rhamnose is critical for the biosynthesis of the Group A Carbohydrate, the molecular signature and virulence determinant of the human pathogen Group A S treptococcus (GAS). The final step of the four‐step dTDP‐L‐rhamnose biosynthesis pathway is catalyzed by dTDP‐4‐dehydro...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832382/ https://www.ncbi.nlm.nih.gov/pubmed/26278404 http://dx.doi.org/10.1111/mmi.13169 |