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Phenotypic, Functional, and Gene Expression Profiling of Peripheral CD45RA+ and CD45RO+ CD4+CD25+CD127(low) Treg Cells in Patients With Chronic Rheumatoid Arthritis

OBJECTIVE: Conflicting evidence exists regarding the suppressive capacity of Treg cells in the peripheral blood (PB) of patients with rheumatoid arthritis (RA). The aim of this study was to determine whether Treg cells are intrinsically defective in RA. METHODS: Using a range of assays on PB samples...

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Detalles Bibliográficos
Autores principales:	Walter, Gina J., Fleskens, Veerle, Frederiksen, Klaus S., Rajasekhar, Megha, Menon, Bina, Gerwien, Jens G., Evans, Hayley G., Taams, Leonie S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Rheumatoid Arthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832388/ https://www.ncbi.nlm.nih.gov/pubmed/26314565 http://dx.doi.org/10.1002/art.39408

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