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Oncogene swap as a novel mechanism of acquired resistance to epidermal growth factor receptor‐tyrosine kinase inhibitor in lung cancer
Mutant selective epidermal growth factor receptor‐tyrosine kinase inhibitors (EGFR‐TKIs), such as rociletinib and AZD9291, are effective for tumors with T790M secondary mutation that become refractory to first‐generation EGFR‐TKI. However, acquired resistance to these prospective drugs is anticipate...
Autores principales: | Mizuuchi, Hiroshi, Suda, Kenichi, Murakami, Isao, Sakai, Kazuko, Sato, Katsuaki, Kobayashi, Yoshihisa, Shimoji, Masaki, Chiba, Masato, Sesumi, Yuichi, Tomizawa, Kenji, Takemoto, Toshiki, Sekido, Yoshitaka, Nishio, Kazuto, Mitsudomi, Tetsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832847/ https://www.ncbi.nlm.nih.gov/pubmed/26845230 http://dx.doi.org/10.1111/cas.12905 |
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