Cargando…
Anti‐bevacizumab idiotype antibody vaccination is effective in inducing vascular endothelial growth factor‐binding response, impairing tumor outgrowth
Tumors require blood supply and, to overcome this restriction, induce angiogenesis. Vascular endothelial growth factor (VEGF) plays an important role in this process, which explains the great number of antiangiogenic therapies targeting VEGF. The research and development of targeted therapy has led...
Autores principales: | Sanches, Jéssica de Souza, de Aguiar, Rodrigo Barbosa, Parise, Carolina Bellini, Suzuki, Juliana Mayumi, Chammas, Roger, de Moraes, Jane Zveiter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832859/ https://www.ncbi.nlm.nih.gov/pubmed/27079440 http://dx.doi.org/10.1111/cas.12903 |
Ejemplares similares
-
Exploring the Immunological Mechanisms Underlying the Anti-vascular Endothelial Growth Factor Activity in Tumors
por: de Aguiar, Rodrigo Barbosa, et al.
Publicado: (2019) -
Potential of an anti-bevacizumab idiotype scFv DNA-based immunization to elicit VEGF-binding antibody response
por: Silva, Tábata Almeida, et al.
Publicado: (2022) -
Idiotype-recognizing T helper cells that are not idiotype specific
Publicado: (1983) -
Idiotypic regulation of the immune system. Common idiotypic specificities between idiotypes and antibodies raised against anti- idiotypic antibodies in rabbits
Publicado: (1979) -
Idiotype-anti-idiotype network. II. Activation of silent clones by treatment at birth with idiotypes is associated with the expansion of idiotype-specific helper T cells
Publicado: (1982)