Enhanced gefitinib‐induced repression of the epidermal growth factor receptor pathway by ataxia telangiectasia‐mutated kinase inhibition in non‐small‐cell lung cancer cells

The epidermal growth factor receptor (EGFR) tyrosine kinase signaling pathways regulate cellular activities. The EGFR tyrosine kinase inhibitors (EGFR‐TKIs) repress the EGFR pathway constitutively activated by somatic EGFR gene mutations and have drastically improved the prognosis of non‐small‐cell...

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Detalles Bibliográficos
Autores principales: Misumi, Keizo, Sun, Jiying, Kinomura, Aiko, Miyata, Yoshihiro, Okada, Morihito, Tashiro, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832868/
https://www.ncbi.nlm.nih.gov/pubmed/26825989
http://dx.doi.org/10.1111/cas.12899

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