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Rad7 E3 Ubiquitin Ligase Attenuates Polyubiquitylation of Rpn10 and Dsk2 Following DNA Damage in Saccharomyces cerevisiae

During Nucleotide Excision Repair (NER) in the yeast S. cerevisiae, ubiquitylation of Rad4 is carried out by the E3 ubiquitin ligase that includes Rad7-Elc1-Cul3 and is critical to optimal NER. Rad7 E3 activity targets Rad4 for degradation by the proteaseome but, in principle, could also trigger oth...

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Detalles Bibliográficos
Autores principales:	Benoun, Joseph M., Lalimar-Cortez, Danielle, Valencia, Analila, Granda, Adriana, Moore, Destaye M., Kelson, Eric P., Fischhaber, Paula L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832922/ https://www.ncbi.nlm.nih.gov/pubmed/27092291 http://dx.doi.org/10.4236/abc.2015.57021

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