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Evidence That the Capacity of Nongenotoxic Carcinogens to Induce Oxidative Stress Is Subject to Marked Variability

Many drugs and environmental chemicals which are not directly mutagenic have the capacity to increase the incidence of tumors in the liver and other tissues. For this reason, such compounds are known as nongenotoxic carcinogens. The mechanisms underlying their effects remain unclear; however, their...

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Detalles Bibliográficos
Autores principales: Henderson, Colin J., Cameron, Amy R., Chatham, Lynsey, Stanley, Lesley A., Wolf, Charles Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833039/
https://www.ncbi.nlm.nih.gov/pubmed/25690736
http://dx.doi.org/10.1093/toxsci/kfv039