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Data supporting the role of Fyn in initiating myelination in the peripheral nervous system
Transgenic mice, which express active Fyn tyrosine kinase under the control of a glial fibrillary acidic protein promoter, have been produced. This promoter induces protein expression in the initiation stage of myelination in the peripheral nervous system (PNS) “Phosphorylation of cytohesin-1 by Fyn...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833127/ https://www.ncbi.nlm.nih.gov/pubmed/27115022 http://dx.doi.org/10.1016/j.dib.2016.03.096 |
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author | Miyamoto, Yuki Tamano, Moe Torii, Tomohiro Kawahara, Kazuko Nakamura, Kazuaki Tanoue, Akito Takada, Shuji Yamauchi, Junji |
author_facet | Miyamoto, Yuki Tamano, Moe Torii, Tomohiro Kawahara, Kazuko Nakamura, Kazuaki Tanoue, Akito Takada, Shuji Yamauchi, Junji |
author_sort | Miyamoto, Yuki |
collection | PubMed |
description | Transgenic mice, which express active Fyn tyrosine kinase under the control of a glial fibrillary acidic protein promoter, have been produced. This promoter induces protein expression in the initiation stage of myelination in the peripheral nervous system (PNS) “Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development (Yamauchi et al., 2015 [1])”. Herein we provide the data regarding myelination-related protein markers and myelin ultrastructure in transgenic mice. |
format | Online Article Text |
id | pubmed-4833127 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-48331272016-04-25 Data supporting the role of Fyn in initiating myelination in the peripheral nervous system Miyamoto, Yuki Tamano, Moe Torii, Tomohiro Kawahara, Kazuko Nakamura, Kazuaki Tanoue, Akito Takada, Shuji Yamauchi, Junji Data Brief Data Article Transgenic mice, which express active Fyn tyrosine kinase under the control of a glial fibrillary acidic protein promoter, have been produced. This promoter induces protein expression in the initiation stage of myelination in the peripheral nervous system (PNS) “Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development (Yamauchi et al., 2015 [1])”. Herein we provide the data regarding myelination-related protein markers and myelin ultrastructure in transgenic mice. Elsevier 2016-04-01 /pmc/articles/PMC4833127/ /pubmed/27115022 http://dx.doi.org/10.1016/j.dib.2016.03.096 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Data Article Miyamoto, Yuki Tamano, Moe Torii, Tomohiro Kawahara, Kazuko Nakamura, Kazuaki Tanoue, Akito Takada, Shuji Yamauchi, Junji Data supporting the role of Fyn in initiating myelination in the peripheral nervous system |
title | Data supporting the role of Fyn in initiating myelination in the peripheral nervous system |
title_full | Data supporting the role of Fyn in initiating myelination in the peripheral nervous system |
title_fullStr | Data supporting the role of Fyn in initiating myelination in the peripheral nervous system |
title_full_unstemmed | Data supporting the role of Fyn in initiating myelination in the peripheral nervous system |
title_short | Data supporting the role of Fyn in initiating myelination in the peripheral nervous system |
title_sort | data supporting the role of fyn in initiating myelination in the peripheral nervous system |
topic | Data Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833127/ https://www.ncbi.nlm.nih.gov/pubmed/27115022 http://dx.doi.org/10.1016/j.dib.2016.03.096 |
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