Progesterone promotes maternal–fetal tolerance by reducing human maternal T‐cell polyfunctionality and inducing a specific cytokine profile

Progesterone is a steroid hormone essential for the maintenance of human pregnancy, and its actions are thought to include promoting maternal immune tolerance of the semiallogenic fetus. We report that exposure of maternal T cells to progesterone at physiological doses induced a unique skewing of th...

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Detalles Bibliográficos
Autores principales: Lissauer, David, Eldershaw, Suzy A., Inman, Charlotte F., Coomarasamy, Aravinthan, Moss, Paul A. H., Kilby, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Immunomodulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833190/
https://www.ncbi.nlm.nih.gov/pubmed/26249148
http://dx.doi.org/10.1002/eji.201445404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833190/
https://www.ncbi.nlm.nih.gov/pubmed/26249148
http://dx.doi.org/10.1002/eji.201445404

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