Andrographolide inhibits growth of human T-cell acute lymphoblastic leukemia Jurkat cells by downregulation of PI3K/AKT and upregulation of p38 MAPK pathways

T-cell acute lymphoblastic leukemia (T-ALL) as a prevalent hematologic malignancy is one of the most common malignant tumors worldwide in children. Andrographolide (Andro), the major active component from Andrographis paniculata, has been shown to possess antitumor activities in several types of can...

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Detalles Bibliográficos
Autores principales: Yang, Tingfang, Yao, Shuluan, Zhang, Xianfeng, Guo, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833376/
https://www.ncbi.nlm.nih.gov/pubmed/27114702
http://dx.doi.org/10.2147/DDDT.S94983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833376/
https://www.ncbi.nlm.nih.gov/pubmed/27114702
http://dx.doi.org/10.2147/DDDT.S94983

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