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A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers
Gross chromosomal rearrangements (GCRs) play an important role in human diseases, including cancer. The identity of all Genome Instability Suppressing (GIS) genes is not currently known. Here multiple Saccharomyces cerevisiae GCR assays and query mutations were crossed into arrays of mutants to iden...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833866/ https://www.ncbi.nlm.nih.gov/pubmed/27071721 http://dx.doi.org/10.1038/ncomms11256 |