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A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers

Gross chromosomal rearrangements (GCRs) play an important role in human diseases, including cancer. The identity of all Genome Instability Suppressing (GIS) genes is not currently known. Here multiple Saccharomyces cerevisiae GCR assays and query mutations were crossed into arrays of mutants to iden...

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Detalles Bibliográficos
Autores principales:	Putnam, Christopher D., Srivatsan, Anjana, Nene, Rahul V., Martinez, Sandra L., Clotfelter, Sarah P., Bell, Sara N., Somach, Steven B., E.S. de Souza, Jorge, Fonseca, André F., de Souza, Sandro J., Kolodner, Richard D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833866/ https://www.ncbi.nlm.nih.gov/pubmed/27071721 http://dx.doi.org/10.1038/ncomms11256

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