Cargando…

MicroRNA-7 targets Nod-like receptor protein 3 inflammasome to modulate neuroinflammation in the pathogenesis of Parkinson’s disease

BACKGROUND: α-Synuclein (α-Syn), a pathological hallmark of Parkinson’s disease (PD), has been recognized to induce the production of interleukin-1β in a process that depends, at least in vitro, on nod-like receptor protein 3 (NLRP3) inflammasome in monocytes. However, the role of NLRP3 inflammasome...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Yan, Lu, Ming, Du, Ren-Hong, Qiao, Chen, Jiang, Chun-Yi, Zhang, Ke-Zhong, Ding, Jian-Hua, Hu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833896/
https://www.ncbi.nlm.nih.gov/pubmed/27084336
http://dx.doi.org/10.1186/s13024-016-0094-3