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MicroRNA-7 targets Nod-like receptor protein 3 inflammasome to modulate neuroinflammation in the pathogenesis of Parkinson’s disease
BACKGROUND: α-Synuclein (α-Syn), a pathological hallmark of Parkinson’s disease (PD), has been recognized to induce the production of interleukin-1β in a process that depends, at least in vitro, on nod-like receptor protein 3 (NLRP3) inflammasome in monocytes. However, the role of NLRP3 inflammasome...
Autores principales: | Zhou, Yan, Lu, Ming, Du, Ren-Hong, Qiao, Chen, Jiang, Chun-Yi, Zhang, Ke-Zhong, Ding, Jian-Hua, Hu, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833896/ https://www.ncbi.nlm.nih.gov/pubmed/27084336 http://dx.doi.org/10.1186/s13024-016-0094-3 |
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