Molecular treatment effects of alemtuzumab in skeletal muscles of patients with IBM

BACKGROUND: Mechanisms of inflammation and protein accumulation are crucial in inclusion body myositis (IBM). Recent evidence demonstrated that intravenous immunoglobulin failed to suppress cell-stress mediators in IBM. Here we studied the molecular changes in skeletal muscle biopsies from patients...

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Detalles Bibliográficos
Autores principales: Schmidt, Karsten, Kleinschnitz, Konstanze, Rakocevic, Goran, Dalakas, Marinos C., Schmidt, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833914/
https://www.ncbi.nlm.nih.gov/pubmed/27083892
http://dx.doi.org/10.1186/s12883-016-0568-5

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