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Prohibitin overexpression predicts poor prognosis and promotes cell proliferation and invasion through ERK pathway activation in gallbladder cancer

BACKGROUND: Prohibitin (PHB), a pleiotropic protein overexpressed in several tumor types, has been implicated in the regulation of cell proliferation, invasive migration and survival. However, PHB expression and its biological function in gallbladder cancer (GBC) remain largely unknown. METHODS: PHB...

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Detalles Bibliográficos
Autores principales: Cao, Yang, Liang, Haibin, Zhang, Fei, Luan, Zhou, Zhao, Shuai, Wang, Xu-an, Liu, Shibo, Bao, Runfa, Shu, Yijun, Ma, Qiang, Zhu, Jian, Liu, Yingbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833931/
https://www.ncbi.nlm.nih.gov/pubmed/27084680
http://dx.doi.org/10.1186/s13046-016-0346-7

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