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OSKM Induce Extraembryonic Endoderm Stem Cells in Parallel to Induced Pluripotent Stem Cells

The reprogramming factors OCT4, SOX2, KLF4, and MYC (OSKM) can reactivate the pluripotency network in terminally differentiated cells, but also regulate expression of non-pluripotency genes in other contexts, such as the mouse primitive endoderm. The primitive endoderm is an extraembryonic lineage e...

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Detalles Bibliográficos
Autores principales: Parenti, Anthony, Halbisen, Michael A., Wang, Kai, Latham, Keith, Ralston, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834035/
https://www.ncbi.nlm.nih.gov/pubmed/26947975
http://dx.doi.org/10.1016/j.stemcr.2016.02.003