Estradiol Facilitates Functional Integration of iPSC-Derived Dopaminergic Neurons into Striatal Neuronal Circuits via Activation of Integrin α5β1

For cell transplantation therapy for Parkinson's disease (PD) to be realized, the grafted neurons should be integrated into the host neuronal circuit to restore the lost neuronal function. Here, using wheat-germ agglutinin-based transsynaptic tracing, we show that integrin α5 is selectively exp...

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Detalles Bibliográficos
Autores principales: Nishimura, Kaneyasu, Doi, Daisuke, Samata, Bumpei, Murayama, Shigeo, Tahara, Tsuyoshi, Onoe, Hirotaka, Takahashi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834042/
https://www.ncbi.nlm.nih.gov/pubmed/26997644
http://dx.doi.org/10.1016/j.stemcr.2016.02.008

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