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Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor

Direct conversion of somatic cells into neural stem cells (NSCs) by defined factors holds great promise for mechanistic studies, drug screening, and potential cell therapies for different neurodegenerative diseases. Here, we report that a single zinc-finger transcription factor, Zfp521, is sufficien...

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Detalles Bibliográficos
Autores principales:	Shahbazi, Ebrahim, Moradi, Sharif, Nemati, Shiva, Satarian, Leila, Basiri, Mohsen, Gourabi, Hamid, Zare Mehrjardi, Narges, Günther, Patrick, Lampert, Angelika, Händler, Kristian, Hatay, Firuze Fulya, Schmidt, Diana, Molcanyi, Marek, Hescheler, Jürgen, Schultze, Joachim L., Saric, Tomo, Baharvand, Hossein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834053/ https://www.ncbi.nlm.nih.gov/pubmed/27052315 http://dx.doi.org/10.1016/j.stemcr.2016.02.013

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