Recombinant fibromodulin has therapeutic effects on diabetic nephropathy by down-regulating transforming growth factor-β1 in streptozotocin-induced diabetic rat model

OBJECTIVE(S): Diabetic nephropathy is an important long-term complication of diabetes mellitus which appears to be partially mediated by an increase in secretion of transforming growth factor-β (TGF-β). Fibromodulin, the small leucine-rich proteoglycan, has been proposed to be the potent TGFβ1 modul...

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Detalles Bibliográficos
Autores principales: Jazi, Maryam Foroutan, Biglari, Alireza, Mazloomzadeh, Saeideh, Kingston, Paul, Ramazani, Ali, Bazzaz, Javad Tavkoli, Eskandari, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834116/
https://www.ncbi.nlm.nih.gov/pubmed/27114796

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