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A U1 snRNP-Specific Assembly Pathway Reveals the SMN Complex as a Versatile RNP Exchange

Despite their equal stoichiometry in spliceosomes, U1 snRNP (U1) is typically the most abundant snRNP in vertebrates. What regulates U1 over-abundance and snRNP repertoire in general is unknown. Sm core assembly is a key step in snRNP biogenesis mediated by the SMN complex. All pre-snRNAs are delive...

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Detalles Bibliográficos
Autores principales:	So, Byung Ran, Wan, Lili, Zhang, Zhenxi, Li, Pilong, Babiash, Eric, Duan, Jingqi, Younis, Ihab, Dreyfuss, Gideon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834709/ https://www.ncbi.nlm.nih.gov/pubmed/26828962 http://dx.doi.org/10.1038/nsmb.3167

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