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Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non‐adherent to CPAP
The aim of this retrospective study was to evaluate the effect of individually adjusted custom‐made mandibular advancement device/oral appliance (OA) in treatment of patients with moderate and severe obstructive sleep apnoea (OSA), who were non‐adherent to continuous positive airway pressure (CPAP)...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834725/ https://www.ncbi.nlm.nih.gov/pubmed/26707632 http://dx.doi.org/10.1111/joor.12376 |
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author | Gjerde, K. Lehmann, S. Berge, M. E. Johansson, A.‐K. Johansson, A. |
author_facet | Gjerde, K. Lehmann, S. Berge, M. E. Johansson, A.‐K. Johansson, A. |
author_sort | Gjerde, K. |
collection | PubMed |
description | The aim of this retrospective study was to evaluate the effect of individually adjusted custom‐made mandibular advancement device/oral appliance (OA) in treatment of patients with moderate and severe obstructive sleep apnoea (OSA), who were non‐adherent to continuous positive airway pressure (CPAP) therapy. During 2007‐2013, 116 patients with moderate (n = 82) and severe (n = 34) OSA non‐adherent to CPAP treatment were referred for dental management with an individually adjusted OA at a specialist sleep clinic. Ten of the participants (8·6%) were lost to follow‐up, leaving the data set to consist of 106 patients (71 men/35 women, mean age 57 year, range 28‐90). Nocturnal respiratory polygraphic recordings were performed at baseline and follow‐up. Average time between baseline polygraphy and follow‐up was 12 months. A successful OA treatment outcome was based on polygraphy at the follow‐up and divided into three groups: 1 = AHI <5; 2 = 5 ≤ AHI <10 and >50% reduction in baseline AHI; and 3. >50% reduction in baseline AHI. If there was a ≤ 50% reduction in baseline AHI at the follow‐up, the treatment was considered as a failure. The overall treatment success rate was 75%. There was no significant difference in success rates between patients in the moderate and severe categories (69% and 77%, respectively). Low oxygen saturation (SpO(2 nadir)) had a high predictive value for OA treatment failure. OA treatment of patients non‐adherent to CPAP is efficient and especially promising for the severe OSA group who are at greatest risks for developing serious comorbidities, if left untreated. |
format | Online Article Text |
id | pubmed-4834725 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-48347252016-05-05 Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non‐adherent to CPAP Gjerde, K. Lehmann, S. Berge, M. E. Johansson, A.‐K. Johansson, A. J Oral Rehabil Original Articles The aim of this retrospective study was to evaluate the effect of individually adjusted custom‐made mandibular advancement device/oral appliance (OA) in treatment of patients with moderate and severe obstructive sleep apnoea (OSA), who were non‐adherent to continuous positive airway pressure (CPAP) therapy. During 2007‐2013, 116 patients with moderate (n = 82) and severe (n = 34) OSA non‐adherent to CPAP treatment were referred for dental management with an individually adjusted OA at a specialist sleep clinic. Ten of the participants (8·6%) were lost to follow‐up, leaving the data set to consist of 106 patients (71 men/35 women, mean age 57 year, range 28‐90). Nocturnal respiratory polygraphic recordings were performed at baseline and follow‐up. Average time between baseline polygraphy and follow‐up was 12 months. A successful OA treatment outcome was based on polygraphy at the follow‐up and divided into three groups: 1 = AHI <5; 2 = 5 ≤ AHI <10 and >50% reduction in baseline AHI; and 3. >50% reduction in baseline AHI. If there was a ≤ 50% reduction in baseline AHI at the follow‐up, the treatment was considered as a failure. The overall treatment success rate was 75%. There was no significant difference in success rates between patients in the moderate and severe categories (69% and 77%, respectively). Low oxygen saturation (SpO(2 nadir)) had a high predictive value for OA treatment failure. OA treatment of patients non‐adherent to CPAP is efficient and especially promising for the severe OSA group who are at greatest risks for developing serious comorbidities, if left untreated. John Wiley and Sons Inc. 2015-12-27 2016-04 /pmc/articles/PMC4834725/ /pubmed/26707632 http://dx.doi.org/10.1111/joor.12376 Text en © 2015 The Authors. Journal of Oral Rehabilitation Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Original Articles Gjerde, K. Lehmann, S. Berge, M. E. Johansson, A.‐K. Johansson, A. Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non‐adherent to CPAP |
title | Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non‐adherent to CPAP
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title_full | Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non‐adherent to CPAP
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title_fullStr | Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non‐adherent to CPAP
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title_full_unstemmed | Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non‐adherent to CPAP
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title_short | Oral appliance treatment in moderate and severe obstructive sleep apnoea patients non‐adherent to CPAP
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title_sort | oral appliance treatment in moderate and severe obstructive sleep apnoea patients non‐adherent to cpap |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834725/ https://www.ncbi.nlm.nih.gov/pubmed/26707632 http://dx.doi.org/10.1111/joor.12376 |
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