Phase I Clinical Trial of 4-1BB-based Adoptive T-Cell Therapy for Epstein-Barr Virus (EBV)-positive Tumors

Although adoptive cell therapy using Ag-specific T cells has been tested successfully in the clinic, the production of these T cells has been challenging. By applying our simple and practical 4-1BB-based method for the generation of Ag-specific CD8(+) T cells, here we determined the maximum tolerate...

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Detalles Bibliográficos
Autores principales: Eom, Hyeon-Seok, Choi, Beom K., Lee, Youngjoo, Lee, Hyewon, Yun, Tak, Kim, Young H., Lee, Je-Jung, Kwon, Byoung S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Clinical Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834812/
https://www.ncbi.nlm.nih.gov/pubmed/26938947
http://dx.doi.org/10.1097/CJI.0000000000000113

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