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T cell fate and clonality inference from single cell transcriptomes

The enormous sequence diversity within T cell receptor (TCR) repertoires allows specific TCR sequences to be used as lineage markers for T cells that derive from a common progenitor. We have developed a computational method, called TraCeR, to reconstruct full-length, paired TCR sequences from T lymp...

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Detalles Bibliográficos
Autores principales:	Stubbington, Michael J.T., Lönnberg, Tapio, Proserpio, Valentina, Clare, Simon, Speak, Anneliese O., Dougan, Gordon, Teichmann, Sarah A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835021/ https://www.ncbi.nlm.nih.gov/pubmed/26950746 http://dx.doi.org/10.1038/nmeth.3800

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