Cargando…

Globular Head-Displayed Conserved Influenza H1 Hemagglutinin Stalk Epitopes Confer Protection against Heterologous H1N1 Virus

Significant genetic variability in the head region of the influenza A hemagglutinin, the main target of current vaccines, makes it challenging to develop a long-lived seasonal influenza prophylaxis. Vaccines based on the conserved hemagglutinin stalk domain might provide broader cross-reactive immun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klausberger, Miriam, Tscheliessnig, Rupert, Neff, Silke, Nachbagauer, Raffael, Wohlbold, Teddy John, Wilde, Monika, Palmberger, Dieter, Krammer, Florian, Jungbauer, Alois, Grabherr, Reingard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835069/ https://www.ncbi.nlm.nih.gov/pubmed/27088239 http://dx.doi.org/10.1371/journal.pone.0153579

Ejemplares similares

An immuno-assay to quantify influenza virus hemagglutinin with correctly folded stalk domains in vaccine preparations
por: Rajendran, Madhusudan, et al.
Publicado: (2018)

Tnao38, high five and Sf9—evaluation of host–virus interactions in three different insect cell lines: baculovirus production and recombinant protein expression
por: Wilde, Monika, et al.
Publicado: (2013)

Development of a Dual-Vector System Utilizing MicroRNA Mimics of the Autographa californica miR-1 for an Inducible Knockdown in Insect Cells
por: Koczka, Krisztina, et al.
Publicado: (2019)

One-shot vaccination with an insect cell-derived low-dose influenza A H7 virus-like particle preparation protects mice against H7N9 challenge()
por: Klausberger, Miriam, et al.
Publicado: (2014)

Age Dependence and Isotype Specificity of Influenza Virus Hemagglutinin Stalk-Reactive Antibodies in Humans
por: Nachbagauer, Raffael, et al.
Publicado: (2016)

Glycosylation Focuses Sequence Variation in the Influenza A Virus H1 Hemagglutinin Globular Domain
por: Das, Suman R., et al.
Publicado: (2010)

Vaccination with Adjuvanted Recombinant Neuraminidase Induces Broad Heterologous, but Not Heterosubtypic, Cross-Protection against Influenza Virus Infection in Mice
por: Wohlbold, Teddy John, et al.
Publicado: (2015)

Cross-reactive mouse monoclonal antibodies raised against the hemagglutinin of A/Shanghai/1/2013 (H7N9) protect against novel H7 virus isolates in the mouse model
por: Stadlbauer, Daniel, et al.
Publicado: (2018)

Cryo-electron Microscopy Structures of Chimeric Hemagglutinin Displayed on a Universal Influenza Vaccine Candidate
por: Tran, Erin E. H., et al.
Publicado: (2016)

Natural and directed antigenic drift of the H1 influenza virus hemagglutinin stalk domain
por: Anderson, Christopher S., et al.
Publicado: (2017)

A universal influenza virus vaccine candidate confers protection against pandemic H1N1 infection in preclinical ferret studies
por: Nachbagauer, Raffael, et al.
Publicado: (2017)

Assessing the Protective Potential of H1N1 Influenza Virus Hemagglutinin Head and Stalk Antibodies in Humans
por: Christensen, Shannon R., et al.
Publicado: (2019)

Publisher Correction: Natural and directed antigenic drift of the H1 influenza virus hemagglutinin stalk domain
por: Anderson, Christopher S., et al.
Publicado: (2018)

Publisher Correction: Natural and directed antigenic drift of the H1 influenza virus hemagglutinin stalk domain
por: Anderson, Christopher S., et al.
Publicado: (2018)

Hemagglutinin Stalk Antibody Responses Following Trivalent Inactivated Influenza Vaccine Immunization of Pregnant Women and Association With Protection From Influenza Virus Illness
por: Dhar, Nisha, et al.
Publicado: (2020)

Broadly Neutralizing Hemagglutinin Stalk-Specific Antibodies Induce Potent Phagocytosis of Immune Complexes by Neutrophils in an Fc-Dependent Manner
por: Mullarkey, Caitlin E., et al.
Publicado: (2016)

Properly Folded Bacterially Expressed H1N1 Hemagglutinin Globular Head and Ectodomain Vaccines Protect Ferrets against H1N1 Pandemic Influenza Virus
por: Khurana, Surender, et al.
Publicado: (2010)

In the Shadow of Hemagglutinin: A Growing Interest in Influenza Viral Neuraminidase and Its Role as a Vaccine Antigen
por: Wohlbold, Teddy John, et al.
Publicado: (2014)

Influenza Virus Hemagglutinin Stalk-Specific Antibodies in Human Serum are a Surrogate Marker for In Vivo Protection in a Serum Transfer Mouse Challenge Model
por: Jacobsen, Henning, et al.
Publicado: (2017)

Hemagglutinin Receptor Binding of a Human Isolate of Influenza A(H10N8) Virus
por: Ramos, Irene, et al.
Publicado: (2015)

Immunogenicity of modified vaccinia virus Ankara expressing the hemagglutinin stalk domain of pandemic (H1N1) 2009 influenza virus
por: Di Mario, Giuseppina, et al.
Publicado: (2017)

A single-shot adenoviral vaccine provides hemagglutinin stalk-mediated protection against heterosubtypic influenza challenge in mice
por: Bliss, Carly M., et al.
Publicado: (2022)

Pandemic influenza virus vaccines boost hemagglutinin stalk-specific antibody responses in primed adult and pediatric cohorts
por: Nachbagauer, Raffael, et al.
Publicado: (2019)

Dissecting the hemagglutinin head and stalk-specific IgG antibody response in healthcare workers following pandemic H1N1 vaccination
por: Tete, Sarah M, et al.
Publicado: (2016)

Development and Assessment of a Pooled Serum as Candidate Standard to Measure Influenza A Virus Group 1 Hemagglutinin Stalk-Reactive Antibodies
por: Carreño, Juan Manuel, et al.
Publicado: (2020)

Freely suspended perforated polymer nanomembranes for protein separations
por: Schuster, Christian, et al.
Publicado: (2018)

Evaluation of an inducible knockout system in insect cells based on co-infection and CRISPR/Cas9
por: Hausjell, Christina Sophie, et al.
Publicado: (2023)

Vaccination with a Recombinant H7 Hemagglutinin-Based Influenza Virus Vaccine Induces Broadly Reactive Antibodies in Humans
por: Stadlbauer, Daniel, et al.
Publicado: (2017)

Group 1 and group 2 hemagglutinin stalk antibody response according to age
por: Sánchez-de Prada, Laura, et al.
Publicado: (2023)

Commentary on ‘Dissecting the hemagglutinin head and stalk specific IgG antibody response in healthcare workers following pandemic H1N1 vaccination’
por: Ross, Ted M
Publicado: (2016)

A mosaic hemagglutinin-based influenza virus vaccine candidate protects mice from challenge with divergent H3N2 strains
por: Broecker, Felix, et al.
Publicado: (2019)

SweetBac: A New Approach for the Production of Mammalianised Glycoproteins in Insect Cells
por: Palmberger, Dieter, et al.
Publicado: (2012)

Correction: SweetBac: A New Approach for the Production of Mammalianised Glycoproteins in Insect Cells
por: Palmberger, Dieter, et al.
Publicado: (2012)

Evaluation of Preexisting Anti-Hemagglutinin Stalk Antibody as a Correlate of Protection in a Healthy Volunteer Challenge with Influenza A/H1N1pdm Virus
por: Park, Jae-Keun, et al.
Publicado: (2018)

Glycosylation changes in the globular head of H3N2 influenza hemagglutinin modulate receptor binding without affecting virus virulence
por: Alymova, Irina V., et al.
Publicado: (2016)

A Live-Attenuated Prime, Inactivated Boost Vaccination Strategy with Chimeric Hemagglutinin-Based Universal Influenza Virus Vaccines Provides Protection in Ferrets: A Confirmatory Study
por: Nachbagauer, Raffael, et al.
Publicado: (2018)

Evaluation of the Influenza A Replicon for Transient Expression of Recombinant Proteins in Mammalian Cells
por: Krammer, Florian, et al.
Publicado: (2010)

Characterization of A/H7 influenza virus global antigenic diversity and key determinants in the hemagglutinin globular head mediating A/H7N9 antigenic evolution
por: Kok, Adinda, et al.
Publicado: (2023)

Recombinant influenza H1, H5 and H9 hemagglutinins containing replaced H3 hemagglutinin transmembrane domain showed enhanced heterosubtypic protection in mice
por: Liu, Qiliang, et al.
Publicado: (2014)

Development of an mRNA vaccine against a panel of heterologous H1N1 seasonal influenza viruses using a consensus hemagglutinin sequence
por: Ma, Ning, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_sjbltq8mgmrl82okdblsm7dof1