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Notch Stimulates Both Self-Renewal and Lineage Plasticity in a Subset of Murine CD9(High) Committed Megakaryocytic Progenitors

This study aimed at reinvestigating the controversial contribution of Notch signaling to megakaryocytic lineage development. For that purpose, we combined colony assays and single cells progeny analyses of purified megakaryocyte-erythroid progenitors (MEP) after short-term cultures on recombinant No...

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Detalles Bibliográficos
Autores principales: Weiss-Gayet, Michèle, Starck, Joëlle, Chaabouni, Azza, Chazaud, Bénédicte, Morlé, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835090/
https://www.ncbi.nlm.nih.gov/pubmed/27089435
http://dx.doi.org/10.1371/journal.pone.0153860