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Reactivation of autophagy by spermidine ameliorates the myopathic defects of collagen VI-null mice
Autophagy is a self-degradative process responsible for the clearance of damaged or unnecessary cellular components. We have previously found that persistence of dysfunctional organelles due to autophagy failure is a key event in the pathogenesis of COL6/collagen VI-related myopathies, and have demo...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835186/ https://www.ncbi.nlm.nih.gov/pubmed/26565691 http://dx.doi.org/10.1080/15548627.2015.1108508 |