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Molecular optimization of rabies virus glycoprotein expression in Pichia pastoris

In this work, different approaches were investigated to enhance the expression rabies virus glycoprotein (RABV‐G) in the yeast Pichia pastoris; this membrane protein is responsible for the synthesis of rabies neutralizing antibodies. First, the impact of synonymous codon usage bias was examined and...

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Detalles Bibliográficos
Autores principales: Ben Azoun, Safa, Belhaj, Aicha Eya, Göngrich, Rebecca, Gasser, Brigitte, Kallel, Héla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835572/
https://www.ncbi.nlm.nih.gov/pubmed/26880068
http://dx.doi.org/10.1111/1751-7915.12350