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Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan

Increased production of reactive oxygen species (ROS) has long been considered a cause of aging. However, recent studies have implicated ROS as essential secondary messengers. Here we show that the site of ROS production significantly contributes to their apparent dual nature. We report that ROS inc...

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Detalles Bibliográficos
Autores principales: Scialò, Filippo, Sriram, Ashwin, Fernández-Ayala, Daniel, Gubina, Nina, Lõhmus, Madis, Nelson, Glyn, Logan, Angela, Cooper, Helen M., Navas, Plácido, Enríquez, Jose Antonio, Murphy, Michael P., Sanz, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835580/
https://www.ncbi.nlm.nih.gov/pubmed/27076081
http://dx.doi.org/10.1016/j.cmet.2016.03.009