Cargando…
Mitochondrial ROS Produced via Reverse Electron Transport Extend Animal Lifespan
Increased production of reactive oxygen species (ROS) has long been considered a cause of aging. However, recent studies have implicated ROS as essential secondary messengers. Here we show that the site of ROS production significantly contributes to their apparent dual nature. We report that ROS inc...
Autores principales: | Scialò, Filippo, Sriram, Ashwin, Fernández-Ayala, Daniel, Gubina, Nina, Lõhmus, Madis, Nelson, Glyn, Logan, Angela, Cooper, Helen M., Navas, Plácido, Enríquez, Jose Antonio, Murphy, Michael P., Sanz, Alberto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835580/ https://www.ncbi.nlm.nih.gov/pubmed/27076081 http://dx.doi.org/10.1016/j.cmet.2016.03.009 |
Ejemplares similares
-
Target of rapamycin activation predicts lifespan in fruit flies
por: Scialò, Filippo, et al.
Publicado: (2015) -
Role of Mitochondrial Reverse Electron Transport in ROS Signaling: Potential Roles in Health and Disease
por: Scialò, Filippo, et al.
Publicado: (2017) -
Mitochondrial complex I derived ROS regulate stress adaptation in Drosophila melanogaster
por: Scialò, Filippo, et al.
Publicado: (2020) -
Practical Recommendations for the Use of the GeneSwitch Gal4 System to Knock-Down Genes in Drosophila melanogaster
por: Scialo, Filippo, et al.
Publicado: (2016) -
Mitochondrial ROS production correlates with, but does not directly
regulate lifespan in drosophila
por: Sanz, Alberto, et al.
Publicado: (2010)