Seizure-Induced Regulations of Amyloid-β, STEP(61), and STEP(61) Substrates Involved in Hippocampal Synaptic Plasticity

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline. Pathologic accumulation of soluble amyloid-β (Aβ) oligomers impairs synaptic plasticity and causes epileptic seizures, both of which contribute to cognitive dysfunction in AD. However, wheth...

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Detalles Bibliográficos
Autores principales: Jang, Sung-Soo, Royston, Sara E., Lee, Gunhee, Wang, Shuwei, Chung, Hee Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835651/
https://www.ncbi.nlm.nih.gov/pubmed/27127657
http://dx.doi.org/10.1155/2016/2123748

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