Cargando…

Phosphorylated IGFBP-1 as a non-invasive predictor of liver fat in NAFLD

Insulin-like growth factor binding protein 1 (IGFBP-1) is a potentially interesting marker for liver fat in NAFLD as it is exclusively produced by the liver, and insulin is its main regulator. We determined whether measurement of fasting serum phosphorylated IGFBP-1 (fS-pIGFBP-1) helps to predict li...

Descripción completa

Detalles Bibliográficos
Autores principales:	Petäjä, Elina M., Zhou, You, Havana, Marika, Hakkarainen, Antti, Lundbom, Nina, Ihalainen, Jarkko, Yki-Järvinen, Hannele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835723/ https://www.ncbi.nlm.nih.gov/pubmed/27091074 http://dx.doi.org/10.1038/srep24740

Ejemplares similares

Predictors of Liver Fat and Stiffness in Non-Alcoholic Fatty Liver Disease (NAFLD) – an 11-Year Prospective Study
por: Lallukka, Susanna, et al.
Publicado: (2017)

Definitions of Normal Liver Fat and the Association of Insulin Sensitivity with Acquired and Genetic NAFLD—A Systematic Review
por: Petäjä, Elina M., et al.
Publicado: (2016)

Characterization of different fat depots in NAFLD using inflammation-associated proteome, lipidome and metabolome
por: Lovric, Alen, et al.
Publicado: (2018)

Saturated Fat Is More Metabolically Harmful for the Human Liver Than Unsaturated Fat or Simple Sugars
por: Luukkonen, Panu K., et al.
Publicado: (2018)

Genome-wide blood DNA methylation alterations at regulatory elements and heterochromatic regions in monozygotic twins discordant for obesity and liver fat
por: Ollikainen, Miina, et al.
Publicado: (2015)

Continuous Grading of Early Fibrosis in NAFLD Using Label-Free Imaging: A Proof-of-Concept Study
por: Pirhonen, Juho, et al.
Publicado: (2016)

Abdominal adipose tissue and liver fat imaging in very low birth weight adults born preterm: birth cohort with sibling-controls
por: Kuula, Juho, et al.
Publicado: (2022)

Nutritional Modulation of Non-Alcoholic Fatty Liver Disease and Insulin Resistance
por: Yki-Järvinen, Hannele
Publicado: (2015)

Personal model‐assisted identification of NAD(+) and glutathione metabolism as intervention target in NAFLD
por: Mardinoglu, Adil, et al.
Publicado: (2017)

Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease
por: Hyötyläinen, Tuulia, et al.
Publicado: (2016)

Is There Evidence to Support Use of Premixed or Prandial Insulin Regimens in Insulin-Naive or Previously Insulin-Treated Type 2 Diabetic Patients?
por: Yki-Järvinen, Hannele, et al.
Publicado: (2013)

The quest for the missing links in fatty liver genetics: Deep learning to the rescue!
por: Qadri, Sami, et al.
Publicado: (2022)

Cardiac steatosis and left ventricular function in men with metabolic syndrome
por: Nyman, Kristofer, et al.
Publicado: (2013)

Novel hepatic microRNAs upregulated in human nonalcoholic fatty liver disease
por: Soronen, Jarkko, et al.
Publicado: (2016)

Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease
por: Luukkonen, Panu K., et al.
Publicado: (2020)

Body electrical loss analysis (BELA) in the assessment of visceral fat: a demonstration
por: Blomqvist, Kim H, et al.
Publicado: (2011)

Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects
por: Soronen, Jarkko, et al.
Publicado: (2012)

Liraglutide treatment improves postprandial lipid metabolism and cardiometabolic risk factors in humans with adequately controlled type 2 diabetes: A single‐centre randomized controlled study
por: Matikainen, Niina, et al.
Publicado: (2018)

Prediction of non-alcoholic fatty-liver disease and liver fat content by serum molecular lipids
por: Orešič, Matej, et al.
Publicado: (2013)

IGFBP-2 as a biomarker in NAFLD improves hepatic steatosis: an integrated bioinformatics and experimental study
por: Chen, Xu, et al.
Publicado: (2021)

Overfeeding Saturated Fat Increases LDL (Low-Density Lipoprotein) Aggregation Susceptibility While Overfeeding Unsaturated Fat Decreases Proteoglycan-Binding of Lipoproteins
por: Ruuth, Maija, et al.
Publicado: (2021)

Quantitative PCR provides a simple and accessible method for quantitative microbiota profiling
por: Jian, Ching, et al.
Publicado: (2020)

In vitro Effects of Bacterial Exposure on Secretion of Zonulin Family Peptides and Their Detection in Human Tissue Samples
por: Jian, Ching, et al.
Publicado: (2022)

Influence of Ethnicity on the Accuracy of Non-Invasive Scores Predicting Non-Alcoholic Fatty Liver Disease
por: Xia, Ming-Feng, et al.
Publicado: (2016)

Upregulation of Early and Downregulation of Terminal Pathway Complement Genes in Subcutaneous Adipose Tissue and Adipocytes in Acquired Obesity
por: Kaye, Sanna, et al.
Publicado: (2017)

Global Transcript Profiles of Fat in Monozygotic Twins Discordant for BMI: Pathways behind Acquired Obesity
por: Pietiläinen, Kirsi H, et al.
Publicado: (2008)

Better glycaemic control and less hypoglycaemia with insulin glargine 300 U/mL vs glargine 100 U/mL: 1‐year patient‐level meta‐analysis of the EDITION clinical studies in people with type 2 diabetes
por: Ritzel, Robert, et al.
Publicado: (2017)

Phosphorylated IGFBP-1 in predicting successful vaginal delivery in post-term pregnancy
por: Kosinska-Kaczynska, Katarzyna, et al.
Publicado: (2014)

Early-Onset Diabetic E1-DN Mice Develop Albuminuria and Glomerular Injury Typical of Diabetic Nephropathy
por: Hyvönen, Mervi E., et al.
Publicado: (2015)

OSBP-Related Proteins (ORPs) in Human Adipose Depots and Cultured Adipocytes: Evidence for Impacts on the Adipocyte Phenotype
por: Zhou, You, et al.
Publicado: (2012)

IGFBP-3 reduces eNOS and PKCzeta phosphorylation, leading to lowered VEGF levels
por: Zhang, Qiuhua, et al.
Publicado: (2015)

Perirenal fat thickness and liver fat fraction are independent predictors of MetS in adults with overweight and obesity suspected with NAFLD: a retrospective study
por: Wang, Li, et al.
Publicado: (2023)

Concentrations of Insulin Glargine and Its Metabolites During Long-Term Insulin Therapy in Type 2 Diabetic Patients and Comparison of Effects of Insulin Glargine, Its Metabolites, IGF-I, and Human Insulin on Insulin and IGF-I Receptor Signaling
por: Varewijck, Aimee J., et al.
Publicado: (2013)

Waist Circumference Adjusted for Body Mass Index and Intra-Abdominal Fat Mass
por: Berentzen, Tina Landsvig, et al.
Publicado: (2012)

Genetic Variation in SULF2 Is Associated with Postprandial Clearance of Triglyceride-Rich Remnant Particles and Triglyceride Levels in Healthy Subjects
por: Matikainen, Niina, et al.
Publicado: (2013)

Modified Atkins diet induces subacute selective ragged‐red‐fiber lysis in mitochondrial myopathy patients
por: Ahola, Sofia, et al.
Publicado: (2016)

Distinct contributions of metabolic dysfunction and genetic risk factors in the pathogenesis of non-alcoholic fatty liver disease
por: Luukkonen, Panu K., et al.
Publicado: (2022)

Insulin Growth Factor Binding Protein 7 (IGFBP7)-Related Cancer and IGFBP3 and IGFBP7 Crosstalk
por: Jin, Li, et al.
Publicado: (2020)

The Finnish New Variant of Chlamydia trachomatis with a Single Nucleotide Polymorphism in the 23S rRNA Target Escapes Detection by the Aptima Combo 2 Test
por: Hokynar, Kati, et al.
Publicado: (2019)

Acquired Obesity Is Associated with Changes in the Serum Lipidomic Profile Independent of Genetic Effects – A Monozygotic Twin Study
por: Pietiläinen, Kirsi H., et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_rf4sjrbc0pfe06retuhtbc1tev