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Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway
Resistance to oxaliplatin (OXA) is a complex process affecting the outcomes of metastatic colorectal cancer (CRC) patients treated with this drug. De-regulation of the NF-κB signalling pathway has been proposed as an important mechanism involved in this phenomenon. Here, we show that NF-κB was hyper...
Autores principales: | Ruiz de Porras, Vicenç, Bystrup, Sara, Martínez-Cardús, Anna, Pluvinet, Raquel, Sumoy, Lauro, Howells, Lynne, James, Mark I., Iwuji, Chinenye, Manzano, José Luis, Layos, Laura, Bugés, Cristina, Abad, Albert, Martínez-Balibrea, Eva |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835769/ https://www.ncbi.nlm.nih.gov/pubmed/27091625 http://dx.doi.org/10.1038/srep24675 |
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