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The histone deacetylase inhibitor PCI-24781 as a putative radiosensitizer in pediatric glioblastoma cell lines

BACKGROUND: Glioblastoma (GBM) is considered to be one of the most aggressive tumors of the central nervous system (CNS). Even with the use of modern treatment protocols, the prognosis remains reserved, with children with GBM having a mean survival of 12–15 months. METHODS: In the present study we i...

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Detalles Bibliográficos
Autores principales: de Andrade, Pamela Viani, Andrade, Augusto Faria, de Paula Queiroz, Rosane Gomes, Scrideli, Carlos Alberto, Tone, Luiz Gonzaga, Valera, Elvis Terci
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835828/
https://www.ncbi.nlm.nih.gov/pubmed/27095947
http://dx.doi.org/10.1186/s12935-016-0306-5

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