Cargando…

Metabonomic profiles delineate potential role of glutamate-glutamine cycle in db/db mice with diabetes-associated cognitive decline

BACKGROUND: Diabetes-associated cognition decline is one of central nervous system complications in diabetic mellitus, while its pathogenic mechanism remains unclear. In this study, (1)H nuclear magnetic resonance-based metabonomics and immunohistochemistry was used to explore key metabolic alterati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zheng, Yongquan, Yang, Yunjun, Dong, Baijun, Zheng, Hong, Lin, Xiaodong, Du, Yao, Li, Xiaokun, Zhao, Liangcai, Gao, Hongchang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835835/ https://www.ncbi.nlm.nih.gov/pubmed/27090642 http://dx.doi.org/10.1186/s13041-016-0223-5

Ejemplares similares

Impaired Hippocampal Glutamate and Glutamine Metabolism in the db/db Mouse Model of Type 2 Diabetes Mellitus
por: Andersen, Jens Velde, et al.
Publicado: (2017)

Serum Metabonomic Analysis of Protective Effects of Curcuma aromatica Oil on Renal Fibrosis Rats
por: Zhao, Liangcai, et al.
Publicado: (2014)

ZiBuPiYin Recipe Protects db/db Mice from Diabetes-Associated Cognitive Decline through Improving Multiple Pathological Changes
por: Chen, Jing, et al.
Publicado: (2014)

Active Time-Restricted Feeding Improved Sleep-Wake Cycle in db/db Mice
por: Hou, Tianfei, et al.
Publicado: (2019)

Cosmos DB for MongoDB developers: migrating to Azure Cosmos DB and using the MongoDB API
por: Sharma, Manish
Publicado: (2018)

Zinc Prevents the Development of Diabetic Cardiomyopathy in db/db Mice
por: Wang, Shudong, et al.
Publicado: (2017)

Astragaloside IV ameliorates renal injury in db/db mice
por: Sun, Huili, et al.
Publicado: (2016)

Potent long-acting rhFGF21 analog for treatment of diabetic nephropathy in db/db and DIO mice
por: Zhao, Longwei, et al.
Publicado: (2017)

Modeling the glutamate–glutamine neurotransmitter cycle
por: Shen, Jun
Publicado: (2013)

Metabonomic analysis of potential biomarkers and drug targets involved in diabetic nephropathy mice
por: Wei, Tingting, et al.
Publicado: (2015)

Identification of key metabolic changes in renal interstitial fibrosis rats using metabonomics and pharmacology
por: Zhao, Liangcai, et al.
Publicado: (2016)

“Adjust Zang and arouse spirit” electroacupuncture ameliorates cognitive impairment by reducing endoplasmic reticulum stress in db/db mice
por: Li, Mengyuan, et al.
Publicado: (2023)

Debuncher DB1 (DB2 and DB3): 1 A06 - 000 - 1
por: Boltezar, E
Publicado: (1970)

Debuncher DB1 (DB2 and DB3): I A06-000-1
por: Boltezar, E
Publicado: (1970)

Anti-diabetic activities of catalpol in db/db mice
por: Bao, Qinwen, et al.
Publicado: (2016)

Antidiabetic and Antiobesity Effects of Artemether in db/db Mice
por: Guo, Yu, et al.
Publicado: (2018)

Microbiota-governed microRNA-204 impairs endothelial function and blood pressure decline during inactivity in db/db mice
por: Gaddam, Ravinder Reddy, et al.
Publicado: (2020)

Long-Term Oral Administration of Salidroside Alleviates Diabetic Retinopathy in db/db Mice
por: Yao, Fei, et al.
Publicado: (2022)

Vitamin D(3) alleviates cognitive impairment through regulating inflammatory stress in db/db mice
por: Tan, Xiaomu, et al.
Publicado: (2021)

Gut Microbiota Alteration Is Associated With Cognitive Deficits in Genetically Diabetic (Db/db) Mice During Aging
por: Zhang, Jiawei, et al.
Publicado: (2022)

Berkeley DB
por: New Riders
Publicado: (2001)

ProteomicsDB
por: Schmidt, Tobias, et al.
Publicado: (2018)

MongoDB basics : a quick introduction to MongoDB
por: Hows, David, et al.
Publicado: (2014)

Practical MongoDB: architecting, developing, and administering MongoDB
por: Edward, Shakuntala Gupta, et al.
Publicado: (2015)

Segmentation of the Pathophysiological Stages of Diabetic Changes in the db/db Mouse
por: Yamazaki, Masaki, et al.
Publicado: (2009)

Betaine Alleviates Hypertriglycemia and Tau Hyperphosphorylation in db/db Mice
por: Jung, Ga-young, et al.
Publicado: (2013)

Mibefradil reduces blood glucose concentration in db/db mice
por: Lu, Yujie, et al.
Publicado: (2014)

Effect of Ezetimibe on Insulin Secretion in db/db Diabetic Mice
por: Zhong, Yong, et al.
Publicado: (2012)

Mycophenolate Mofetil Ameliorates Diabetic Nephropathy in db/db Mice
por: Seo, Jung-Woo, et al.
Publicado: (2015)

Neuregulin 1 Improves Glucose Tolerance in db/db Mice
por: Ennequin, Gaël, et al.
Publicado: (2015)

Antihyperglycemic and Antiobesity Effects of JAL2 on db/db Mice
por: Lee, In-Seung, et al.
Publicado: (2016)

Retinal Neurodegeneration in db/db Mice at the Early Period of Diabetes
por: Yang, Qin, et al.
Publicado: (2015)

Impaired Muscle Regeneration in Ob/ob and Db/db Mice
por: Nguyen, Mai-Huong, et al.
Publicado: (2011)

Diabetes Alters Diurnal Rhythm of Electroretinogram in db/db Mice
por: Di, Rong, et al.
Publicado: (2019)

Dapagliflozin protects against nonalcoholic steatohepatitis in db/db mice
por: Qiao, Panshuang, et al.
Publicado: (2022)

1-Deoxynojirimycin Alleviates Liver Injury and Improves Hepatic Glucose Metabolism in db/db Mice
por: Liu, Qingpu, et al.
Publicado: (2016)

Multi-Omics Characterization of Type 2 Diabetes Mellitus-Induced Cognitive Impairment in the db/db Mouse Model
por: Song, Xiaoxuan, et al.
Publicado: (2022)

Glutamine Uptake via SNAT6 and Caveolin Regulates Glutamine–Glutamate Cycle
por: Gandasi, Nikhil R., et al.
Publicado: (2021)

Clopidogrel delays and can reverse diabetic nephropathy pathogenesis in type 2 diabetic db/db mice
por: Li, Hong-Qin, et al.
Publicado: (2022)

Dehydro-Tocotrienol-β Counteracts Oxidative-Stress-Induced Diabetes Complications in db/db Mice
por: Dallner, Gustav, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_cv8c4618pqif15n6ce9mugcs4k