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Polymorphism rs5498 of the ICAM-1 gene affects the progression of carotid atherosclerosis in patients with type 2 diabetes mellitus

BACKGROUND: Adhesion molecules are involved in the development of atherosclerosis. An increased level of the ICAM 1 molecule is associated with numerous inflammatory diseases including atherosclerosis of carotid arteries. The rs5498 (K469E) polymorphism of the ICAM-1 gene leads to an increase in the...

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Detalles Bibliográficos
Autores principales: Popović, Dražen, Starčević, Jovana Nikolajević, Letonja, Marija Šantl, Makuc, Jana, Vujkovac, Andreja Cokan, Pleskovič, Ruda Zorc, Gaspar, Ludovit, Kruzliak, Peter, Petrovič, Danijel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835849/
https://www.ncbi.nlm.nih.gov/pubmed/27090396
http://dx.doi.org/10.1186/s12944-016-0247-y